What is PKD?
For a good understanding of PKD, please read the
article by Dr. Miller on PKD
Genetic testing for PKD
In 2004, UC Davis announced a breakthrough in PKD in persian
related cats. A new DNA test done via cheek swab can identify whether the PKD1
gene is carried in a particular cat.
A very good resource for PKD comes right from the founders at UC
Here, at Archadtz, we
wholeheartedly agree with the statement made on the previous website:
Over 38% of Persian cats
worldwide have PKD. Due to the high
frequency of the disease, it is suggested that elimination of cats with PKD from
breeding programs should be performed SLOWLY and CAREFULLY. Each cat with PKD
has many good and important genes that should be maintained in the population,
thus, mass neuter and spaying is NOT recommended. Most cats live long and
healthy lives and do not suffer greatly from having the PKD mutation. Breeders
should consider their entire breeding program as a whole and may consider to
continue to breed cats with PKD. Breeding negative to positive cats would slowly
eliminate the disease. Cats in subsequent generations that are PKD negative
could be selected to replace inportant lines and particular cats. Ultrasound
testing will determine what cats have mild and severe disease. Although the
inheritance of severity is not understood, continued breeding of mildly affected
cats is a conservation approach.